Could salivary phenylalanine concentrations replace blood concentrations?

Liver phenylalanine hydroxylase activity in relation to blood concentrations of tyrosine and phenylalanine in the rat.

The plasma concentration of phenylalanine and tyrosine decreases in normal rats during the first few postnatal days; subsequently, the concentration of phenylalanine remains more or less constant, whereas that of tyrosine exhibits a high peak on day 13. The basal concentrations of the two amino acids were not altered by injections of thyroxine or cortisol, except in 13-day-old rats, when an inj...

ABO blood groups, secretor status, salivary protein, and serum and salivary immunoglobulin concentrations.

Serum and salivary protein and immunoglobulin concentrations have been measured in people of different ABO blood groups and secretor status. The results have confirmed that salivary protein concentrations vary markedly according to an individual's blood group tending to be particularly high in people of group A, but have failed to show any parallel variation in serum protein concentrations. No ...

Diurnal changes in salivary amino acid concentrations.

It has been suggested that the features of saliva (e.g. fluidity, secretion and amino acid concentration) reflect physiological and psychological state of primates as well as subprimates, however, studies which revealed the relationship between the circadian rhythm and the concentrations of salivary amino acids have been limited. In order to better understand their physiological role, diurnal c...

Salivary reagent stick measures serum ethanol concentrations.

Brain phenylalanine concentrations in phenylketonuria: research and treatment of adults.

OBJECTIVE To assess the effects of 2 pharmacologic interventions (amino acid supplements) on the brain levels of phenylalanine (Phe) in adults with phenylketonuria (PKU). METHODS A prospective study was conducted in an outpatient treatment and follow-up setting. The volunteers who were recruited for the first intervention included 4 subjects with classic PKU. The second intervention included ...